Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22702079 | 0.76 | GAA (0.39) | RECQLGAAKMT2APOLBL3MBTL1 | |
| SCHEMBL22702026 | 0.72 | ADH1B (0.38) | HTTALDH1A1CYP2C9 | |
| SCHEMBL22702024 | 0.71 | EPHX1 (0.35) | POLB | |
| SCHEMBL11528816 | 0.71 | RECQL (0.41) | RECQLGAAKMT2APOLBL3MBTL1 | |
| SCHEMBL11531594 | 0.70 | POLB (0.40) | RECQLGAAKMT2APOLBL3MBTL1 | |
| SCHEMBL11533251 | 0.68 | L3MBTL1 (0.40) | RECQLGAAKMT2APOLBTSHR | |
| SCHEMBL3040960 | 0.67 | ADH1B (0.44) | RECQLGAAKMT2APOLBTSHR | |
| SCHEMBL15298632 | 0.66 | RECQL (0.41) | RECQLGAAKMT2APOLBTSHR | |
| SCHEMBL2901200 | 0.65 | RECQL (0.52) | RECQLGAAKMT2APOLBTSHR | |
| SCHEMBL11214822 | 0.65 | RECQL (0.44) | RECQLGAAKMT2APOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319955-B1 | 6-AMINO-QUINOLINE-3-CARBONITRILS AS COT MODULATORS | GILEAD SCIENCES INC (US) | 2020-11-25 | — | — | EP | disclosed |