Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.57 |
| ▸ | DRD1 | P21728 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 6/20 | 0.56 |
| ▸ | HTR1A | P08908 | 5/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 4/20 | 0.54 |
| ▸ | HTR7 | P34969 | 3/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22702312 | 1.00 | DRD2 (0.57) | DRD2DRD1DRD3HTR1AHTR1D | |
| SCHEMBL14507258 | 0.89 | DRD2 (0.47) | DRD2DRD1DRD3HTR1AHTR1D | |
| SCHEMBL7785759 | 0.89 | DRD2 (0.47) | DRD2DRD1DRD3HTR1AHTR1D | |
| SCHEMBL7785681 | 0.83 | DRD2 (0.43) | DRD2DRD1DRD3HTR1AHTR1D | |
| SCHEMBL7785683 | 0.83 | DRD2 (0.43) | DRD2DRD1DRD3HTR1AHTR1D | |
| SCHEMBL5811739 | 0.75 | DRD2 (0.42) | DRD2DRD1 | |
| SCHEMBL7786294 | 0.74 | DRD2 (0.54) | DRD2DRD3HTR1DHTR1BDRD4 | |
| SCHEMBL8126165 | 0.74 | HTR1D (0.64) | DRD2DRD1DRD3HTR1AHTR1D | |
| SCHEMBL7362530 | 0.73 | DRD2 (1.00) | DRD2DRD1DRD3HTR1ADRD4 | |
| SCHEMBL7788774 | 0.73 | DRD2 (1.00) | DRD2DRD1DRD3HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020234273-A1 | A PROCESS FOR THE MANUFACTURING OF (6AR,10AR)-7-PROPYL-6,6A,7,8,9,10,10A,11-OCTAHYDRO-[1,3]DIOXOLO[4',5':5,6]BENZO[1,2-G]QUINOLINE AND (4AR,10AR)-1-PROPYL-1,2,3,4,4A,5,10,10A-OCTAHYDRO-BENZO[G]QUINOLINE-6,7-DIOL | H. LUNDBECK A/S (DK) | 2020-11-26 | — | — | WO | disclosed |