Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22703276 | 0.83 | KDM4E (0.65) | KDM4EHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7825295 | 0.83 | KDM4E (0.65) | KDM4EHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11108478 | 0.69 | NR3C1 (0.53) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27784542 | 0.69 | KDM4E (0.57) | KDM4EHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11109388 | 0.66 | KDM4E (0.44) | KDM4EHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11215947 | 0.66 | ACHE (0.45) | KDM4EHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7830543 | 0.66 | KDM4E (1.00) | KDM4EHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11107057 | 0.64 | NR3C1 (0.65) | KDM4EHPGDALDH1A1LMNAHSD17B10 | |
| SCHEMBL559163 | 0.64 | PARP1 (0.47) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28851736 | 0.64 | KDM4E (0.50) | KDM4EHPGDSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214493-B | The selective reduction of chirality B catalyst is utilized to prepare (-) α-Noscapine | NANJING ACESYS PHARMATECH CO., LTD. (CN) | 2015-12-23 | — | — | CN | disclosed |
| CN-103214493-A | Method for generating narcotine by selective reduction utilizing chiral boron catalyst | NANJING ACESYS PHARMATECH CO LTD | 2013-07-24 | — | — | CN | disclosed |