Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20234206 | 1.00 | CHRM2 (0.47) | CHRM2CHRM1CHRM3ACHEMTNR1A | |
| SCHEMBL18591751 | 0.88 | MTNR1A (0.40) | CHRM2CHRM1CHRM3ACHEMTNR1A | |
| SCHEMBL18591813 | 0.88 | MTNR1A (0.40) | CHRM2CHRM1CHRM3ACHEMTNR1A | |
| SCHEMBL30230087 | 0.85 | CHRM2 (0.51) | CHRM2CHRM1CHRM3ACHEMTNR1A | |
| SCHEMBL30230412 | 0.85 | CHRM2 (0.51) | CHRM2CHRM1CHRM3ACHEMTNR1A | |
| SCHEMBL20322409 | 0.85 | CHRM2 (0.51) | CHRM2CHRM1CHRM3ACHEMTNR1A | |
| SCHEMBL20233648 | 0.85 | CHRM2 (0.51) | CHRM2CHRM1CHRM3ACHEMTNR1A | |
| SCHEMBL21025847 | 0.77 | MTNR1A (0.44) | ACHEMTNR1AMTNR1BKDM4ENSD2 | |
| SCHEMBL20325681 | 0.77 | MTNR1A (0.44) | ACHEMTNR1AMTNR1BKDM4ENSD2 | |
| SCHEMBL22873373 | 0.76 | MTNR1A (0.38) | CHRM2CHRM1CHRM3ACHEMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020233512-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | 成都海创药业有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |