Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30230087 | 1.00 | CHRM2 (0.51) | CHRM2CHRM1CHRM3MTNR1AMTNR1B | |
| SCHEMBL20233648 | 1.00 | CHRM2 (0.51) | CHRM2CHRM1CHRM3MTNR1AMTNR1B | |
| SCHEMBL30230412 | 1.00 | CHRM2 (0.51) | CHRM2CHRM1CHRM3MTNR1AMTNR1B | |
| SCHEMBL18551050 | 0.88 | MTNR1A (0.47) | CHRM2CHRM1CHRM3MTNR1AMTNR1B | |
| SCHEMBL20234206 | 0.85 | CHRM2 (0.47) | CHRM2CHRM1CHRM3MTNR1AMTNR1B | |
| SCHEMBL22704116 | 0.85 | CHRM2 (0.47) | CHRM2CHRM1CHRM3MTNR1AMTNR1B | |
| SCHEMBL20443287 | 0.84 | MTNR1A (0.44) | CHRM2CHRM1CHRM3MTNR1AMTNR1B | |
| SCHEMBL12881236 | 0.82 | ALOX5 (0.49) | CHRM2CHRM1CHRM3ACHEALOX5 | |
| SCHEMBL22047298 | 0.81 | TAAR1 (0.49) | MTNR1AMTNR1BACHEALOX5CYP2D6 | |
| SCHEMBL18551176 | 0.79 | MTNR1A (0.48) | MTNR1AMTNR1BACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3660004-B1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | ARVINAS OPERATIONS INC (US) | 2023-02-22 | — | — | EP | disclosed |
| WO-2020023851-A1 | BIFUNCTIONAL SUBSTITUED PYRIMIDINES AS MODULATORS OF FAK PROTEOLYSE | YALE UNIVERSITY (US) | 2020-01-30 | — | — | WO | disclosed |
| WO-2019195201-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |
| WO-2018118598-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF FETAL LIVER KINASE POLYPEPTIDES | Arvinas, Inc. (US) | 2018-06-28 | — | — | WO | disclosed |