Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12557539 | 0.69 | — | — | |
| SCHEMBL96652 | 0.68 | OPRK1 (0.34) | OPRK1 | |
| SCHEMBL23101876 | 0.68 | OPRK1 (0.34) | OPRK1 | |
| SCHEMBL12946011 | 0.67 | OPRK1 (0.35) | OPRK1OPRM1OPRD1 | |
| SCHEMBL19343122 | 0.66 | OPRK1 (0.33) | ALDH1A1L3MBTL1OPRK1OPRM1OPRD1 | |
| SCHEMBL19756523 | 0.65 | — | — | |
| SCHEMBL24439229 | 0.62 | — | — | |
| SCHEMBL24260751 | 0.60 | HTR6 (0.38) | — | |
| SCHEMBL24567601 | 0.59 | — | — | |
| SCHEMBL22752058 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020233512-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | 成都海创药业有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |