⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24294347 | 0.82 | — | — | |
| SCHEMBL22704535 | 0.75 | POLB (0.30) | — | |
| SCHEMBL22704533 | 0.73 | POLB (0.31) | — | |
| SCHEMBL22704481 | 0.73 | KDM4E (0.34) | — | |
| SCHEMBL22704503 | 0.71 | KDM4E (0.39) | — | |
| SCHEMBL22704536 | 0.70 | KDM4E (0.34) | — | |
| SCHEMBL22704530 | 0.69 | KDM4E (0.36) | — | |
| SCHEMBL22849851 | 0.67 | NCF1 (0.30) | — | |
| SCHEMBL27284744 | 0.65 | DRD3 (0.34) | — | |
| SCHEMBL26370220 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971176-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | Hinova Pharmaceuticals Inc. (CN) | 2022-03-23 | — | — | EP | disclosed |
| WO-2020233512-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | 成都海创药业有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |