SCHEMBL22705707

SCHEMBL22705707

Cc1ccc(C2(c3ccc(C)cc3)c3ccccc3-c3cccc(-c4c5cccc(-c6ccc7c8ccccc8n(C)c7c6)c5cc5c(-c6ccc7c8ccccc8n(C)c7c6)cccc45)c32)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
KIF11 P52732 1/20 0.33
GPR3 P46089 1/20 0.33
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ALDH1A1 P00352 3/20 0.31
RXFP1 Q9HBX9 2/20 0.31
KDM4E B2RXH2 2/20 0.31
HPGD P15428 2/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
NTRK1 P04629 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22705710 0.94 PSEN1 (0.34) BCHEACHEGPR3L3MBTL1ALDH1A1
SCHEMBL22707717 0.93 RXRA (0.39) RXRARXRBKIF11GPR3NPC1
SCHEMBL22705679 0.90 RXRA (0.39) RXRARXRBKIF11GPR3NPC1
SCHEMBL22706528 0.90 RXRA (0.35) RXRARXRBBCHEACHEKIF11
SCHEMBL22707782 0.89 PSEN1 (0.32) BCHEACHEL3MBTL1ALDH1A1KDM4E
SCHEMBL22706895 0.87 KDM4E (0.35) L3MBTL1ALDH1A1RXFP1KDM4ELMNA
SCHEMBL22706547 0.86 KDM4E (0.36) RXRARXRBGPR3L3MBTL1ALDH1A1
SCHEMBL22705708 0.85 BCHE (0.34) BCHEACHEGPR3L3MBTL1RXFP1
SCHEMBL22705709 0.85 ALKBH5 (0.39) BCHEACHEGPR3RAB9AL3MBTL1
SCHEMBL22705681 0.84 GPR3 (0.38) RXRARXRBBCHEACHEKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed