SCHEMBL2270774

SCHEMBL2270774

CCN(CC)CCC[SiH2]C=CC(C)C

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.34
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2271437 0.71 MEN1 (0.38) SIGMAR1ALDH1A1
SCHEMBL2267485 0.69 KDM1A (0.42)
SCHEMBL2501827 0.68 PAOX (0.33) SIGMAR1ALDH1A1
SCHEMBL435308 0.65 HRH3 (0.35) SIGMAR1ALDH1A1
SCHEMBL16591751 0.65 SIGMAR1 (0.34) SIGMAR1ALDH1A1
SCHEMBL2100127 0.63 SIGMAR1 (0.33) SIGMAR1
SCHEMBL2102357 0.63
SCHEMBL15052279 0.62 SIGMAR1 (0.48) SIGMAR1ALDH1A1
SCHEMBL234338 0.62 SIGMAR1 (0.48) SIGMAR1ALDH1A1
SCHEMBL235041 0.62 SIGMAR1 (0.42) SIGMAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed