Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 6/20 | 0.34 |
| ▸ | CCND1 | P24385 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22708873 | 0.87 | CDK4 (0.34) | CDK4CCND1HPGDHTTSMN1; SMN2 | |
| SCHEMBL22708418 | 0.85 | HPGD (0.45) | CDK4CCND1HPGDHTTSMN1; SMN2 | |
| SCHEMBL22708395 | 0.84 | CDK4 (0.48) | CDK4CCND1HPGDHTTSMN1; SMN2 | |
| SCHEMBL22708507 | 0.82 | GABRP (0.37) | CDK4CCND1GABRPGABRDGABRA1 | |
| SCHEMBL22708610 | 0.80 | GABRP (0.38) | CDK4CCND1GABRPGABRDGABRA1 | |
| SCHEMBL26587874 | 0.79 | ALOX5 (0.39) | SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL26587933 | 0.79 | ALOX5 (0.41) | SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL22708746 | 0.78 | CDK4 (0.40) | CDK4CCND1GABRPGABRDGABRA1 | |
| SCHEMBL26587981 | 0.77 | AKR1B1 (0.35) | HPGDHTTSMN1; SMN2MAPK1WEE1 | |
| SCHEMBL22708880 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11588110-B2 | Heterocyclic compound and organic light emitting device comprising the same | LT MATERIALS CO., LTD. (KR) | 2023-02-21 | — | — | US | disclosed |
| US-20200373499-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | LT MATERIALS CO., LTD. (KR) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11588110-B2 | Heterocyclic compound and organic light emitting device comprising the same | CRY1, CYP1A1, CYP1B1 | CDK4 185/4885CCND1 114/4885HPGD 766/4885 |
| US-20200373499-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | CRY1, CYP1A1, CYP1B1 | CDK4 185/4885CCND1 114/4885HPGD 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.