Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707463 | 0.85 | CYP2C19 (0.48) | HTTKMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL26920242 | 0.78 | HTT (0.46) | HTTKMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL29839043 | 0.78 | HTT (0.46) | HTTKMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL29839055 | 0.78 | HTT (0.46) | HTTKMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL26920776 | 0.75 | FFAR4 (0.46) | HTTKMT2ATSHRMEN1GAA | |
| SCHEMBL26920833 | 0.75 | FFAR4 (0.46) | HTTKMT2ATSHRMEN1GAA | |
| SCHEMBL8560063 | 0.71 | ALDH1A1 (0.44) | HTTTSHRHSD17B10GAAL3MBTL1 | |
| SCHEMBL21151863 | 0.71 | ALDH1A1 (0.58) | HTTSMN1; SMN2MAPTCYP2C19GAA | |
| SCHEMBL8675044 | 0.71 | CHRM2 (0.56) | KMT2ATSHRMEN1HSD17B10CYP2C19 | |
| SCHEMBL27324484 | 0.69 | KCNN4 (0.43) | KMT2ATSHRMEN1MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3142655-B1 | COMPOSITIONS AND METHODS OF TREATING CARDIAC FIBROSIS WITH IFETROBAN | CUMBERLAND PHARMACEUTICALS INC (US) | 2020-12-02 | — | — | EP | disclosed |