Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209643 | 0.80 | MEN1 (0.35) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL22711428 | 0.78 | GPR35 (0.35) | GPR35 | |
| SCHEMBL22711505 | 0.76 | NPC1 (0.37) | GPR35NPC1POLBRAB9A | |
| SCHEMBL23978152 | 0.72 | — | — | |
| SCHEMBL13990270 | 0.70 | — | — | |
| SCHEMBL22711473 | 0.69 | PTPN1 (0.42) | KMT2AGPR35 | |
| SCHEMBL17400910 | 0.68 | — | — | |
| SCHEMBL5516135 | 0.65 | MEN1 (0.36) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL12386832 | 0.65 | PTGS2 (0.35) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL12431900 | 0.65 | PTGS2 (0.38) | MEN1KMT2ANPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655685-B | Thiophene derivative and use thereof | 藤本株式会社 | 2023-11-17 | — | — | CN | disclosed |
| EP-3744719-B1 | THIOPHENE DERIVATIVE AND USE THEREOF | FUJIMOTO CO LTD (JP) | 2023-06-07 | — | — | EP | disclosed |
| US-11299485-B2 | Thiophene derivative and use thereof | FUJIMOTO CO., LTD. (JP) | 2022-04-12 | — | — | US | disclosed |
| US-20210061795-A1 | THIOPHENE DERIVATIVE AND USE THEREOF | FUJIMOTO CO., LTD. (JP) | 2021-03-04 | — | — | US | disclosed |
| EP-3744719-A1 | THIOPHENE DERIVATIVE AND USE THEREOF | Fujimoto Co., Ltd. (JP) | 2020-12-02 | — | — | EP | disclosed |
| CN-111655685-A | Thiophene derivative and use thereof | 藤本株式会社 | 2020-09-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061795-A1 | THIOPHENE DERIVATIVE AND USE THEREOF | TNF, TPMT, CD47 | MEN1 3331/4885KMT2A 2650/4885GPR35 3928/4885 |
| US-11299485-B2 | Thiophene derivative and use thereof | TNF, TPMT, CD47 | MEN1 3331/4885KMT2A 2650/4885GPR35 3928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.