⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5393702 | 0.72 | — | — | |
| SCHEMBL8535240 | 0.71 | NOTUM (0.68) | — | |
| SCHEMBL8340218 | 0.70 | — | — | |
| SCHEMBL6932842 | 0.70 | — | — | |
| SCHEMBL7369068 | 0.67 | NOTUM (0.67) | — | |
| SCHEMBL6930696 | 0.67 | — | — | |
| SCHEMBL8246393 | 0.67 | — | — | |
| SCHEMBL218183 | 0.67 | — | — | |
| SCHEMBL595653 | 0.67 | — | — | |
| SCHEMBL1843023 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743445-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AS DNA POLYMERASE THETA INHIBITORS FOR THE PREVENTION OR TREATMENT OF CANCER | Daewoong Pharmaceutical Co., Ltd. (KR) | 2026-05-20 | — | — | EP | disclosed |
| CN-117024411-B | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | disclosed |
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4642782-A2 | ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF | Pliant Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| US-12448377-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-10-21 | — | — | US | disclosed |
| US-20250313572-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | ABBVIE INC (US) | 2025-10-09 | — | — | US | disclosed |
| EP-4066893-B1 | 6,7,8,9-TETRAHYDRO-4H-QUINOLIZIN-4-ONE COMPOUND AS OREXIN TYPE 2 RECEPTOR AGONIST | TAKEDA PHARMACEUTICALS CO (JP) | 2025-07-30 | — | — | EP | disclosed |
| US-12291523-B2 | LXR modulators with bicyclic core moiety | ORSOBIO, INC. (US) | 2025-05-06 | — | — | US | disclosed |
| WO-2025051157-A1 | PYRIDINE-2(1H)-KETONE PRMT5-MTA INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2025-03-13 | — | — | WO | disclosed |
| US-20250049814-A1 | 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2025-02-13 | — | — | US | disclosed |
| US-6211371-B1 | REACTING AN ARYL ISONIRILE WITH AN ISOQUINOLIN-1-ONE COMPOUND | UNIVERSITY OF PITTSBURGH | 2001-04-03 | — | — | US | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |
| US-6034243-A | Intermediates in the synthesis of (±)-camptothecin and related compounds and synthesis thereof | UNIVERSITY OF PITTSBURGH (US) | 2000-03-07 | — | — | US | disclosed |
| WO-1999001456-A1 | SYNTHESIS OF AND INTERMEDIATES FOR CAMPTOTHECINS | UNIVERSITY OF PITTSBURGH (US) | 1999-01-14 | — | — | WO | disclosed |
| US-5840654-A | COMBATING UNDESIRED PLANT GROWTH BY TREATING LOCUS WITH SPECIFIED HERBICIDE | AMERICAN CYANAMID COMPANY (US) | 1998-11-24 | — | — | US | disclosed |
| US-5744605-A | ANNULATION; CYCLIZATION | UNIVERSITY OF PITTSBURGH (US) | 1998-04-28 | — | — | US | disclosed |
| EP-0690846-B1 | HERBICIDAL HETEROCYCLIC-SUBSTITUTED PYRIDINES | SHELL INT RESEARCH (NL) | 1998-01-07 | — | — | EP | disclosed |
| CN-1122596-A | Herbicidal heterocyclic-substituted pyridines | SHELL INT RESEARCH (NL) | 1996-05-15 | — | — | CN | disclosed |
| EP-0690846-A1 | HERBICIDAL HETEROCYCLIC-SUBSTITUTED PYRIDINES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022833-A1 | HERBICIDAL HETEROCYCLIC-SUBSTITUTED PYRIDINES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-10-13 | — | — | WO | disclosed |