SCHEMBL2271505

SCHEMBL2271505

CCCC[SiH](C=CCl)CCCC

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.30
TDP1 Q9NUW8 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25381519 0.74 LMNA (0.30) TSHRLMNA
SCHEMBL25381613 0.70
SCHEMBL2272773 0.70 ADH1B (0.31) TSHR
SCHEMBL2273518 0.70
SCHEMBL2268577 0.69 ADH1B (0.34) TSHR
SCHEMBL5968696 0.67 TSHR (0.41) TSHRLMNA
SCHEMBL6862599 0.67 TSHR (0.40) TSHRLMNA
SCHEMBL6867458 0.67 TSHR (0.40) TSHRLMNA
SCHEMBL27943139 0.63 TSHR (0.38) TSHRLMNA
SCHEMBL864354 0.61 TSHR (0.40) TSHRTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed