SCHEMBL2272773

SCHEMBL2272773

CCCC[SiH](C=CNC)CCCC

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 2/20 0.31
ADH1C P00326 2/20 0.31
ADH1A P07327 2/20 0.31
ADH7 P40394 2/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
EPHX1 P07099 1/20 0.30
ADH4 P08319 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268577 0.79 ADH1B (0.34) ADH1BADH1CADH1AADH7TSHR
SCHEMBL2274978 0.74
SCHEMBL2272778 0.71
SCHEMBL25381519 0.70 LMNA (0.30) TSHR
SCHEMBL2273446 0.69 SIGMAR1 (0.32)
SCHEMBL25381613 0.67
SCHEMBL2273518 0.67
SCHEMBL5968696 0.64 TSHR (0.41) ALDH1A1TSHR
SCHEMBL6862599 0.63 TSHR (0.40) ALDH1A1TSHR
SCHEMBL6867458 0.63 TSHR (0.40) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed