Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121406 | 0.67 | GRIN2D (0.35) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL18028703 | 0.67 | LMNA (0.34) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL548532 | 0.67 | LMNA (0.34) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL22981789 | 0.65 | — | — | |
| SCHEMBL16930788 | 0.65 | LMNA (0.32) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL16930786 | 0.65 | LMNA (0.32) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL8680357 | 0.65 | GRIN2D (0.44) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL258925 | 0.65 | GRIN2D (0.44) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL1930949 | 0.64 | GRIN2D (0.33) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL16930787 | 0.63 | GRIN2D (0.32) | LMNASLC22A2SLC22A1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107324978-B | Biphenyl substituted adamantane derivative monomolecular resin, positive photoresist composition and negative photoresist composition | 中国科学院理化技术研究所 | 2020-10-02 | — | — | CN | disclosed |
| CN-107266319-B | Dendritic polyphenyl substituted adamantane derivative monomolecular resin, positive photoresist composition and negative photoresist composition | 中国科学院理化技术研究所 | 2020-04-24 | — | — | CN | disclosed |
| US-20110200536-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2011-08-18 | — | — | US | disclosed |
| EP-2178862-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE Healthcare AS (NO) | 2010-04-28 | — | — | EP | disclosed |
| US-20100008864-A1 | AROMATIC MULTIMERS | MEIJER ANDREAS | 2010-01-14 | — | — | US | disclosed |
| WO-2009021948-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2009-02-19 | — | — | WO | disclosed |
| EP-1274755-B1 | LOW DIELECTRIC CONSTANT ORGANIC DIELECTRICS BASED ON CAGE-LIKE STRUCTURES | HONEYWELL INT INC (US) | 2008-02-20 | — | — | EP | disclosed |
| US-7049386-B2 | Compositions and methods for thermosetting molecules in organic compositions | HONEYWELL INTERNATIONAL INC. (US) | 2006-05-23 | — | — | US | disclosed |
| US-20060063834-A1 | Substituted adamantanes, and methods of making the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2006-03-23 | — | — | US | disclosed |
| US-6987147-B2 | Low dielectric constant materials with improved thermo-mechanical strength and processability | HONEYWELL INTERNATIONAL INC. (US) | 2006-01-17 | — | — | US | disclosed |
| EP-1309639-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | Honeywell International, Inc. (US) | 2003-05-14 | — | — | EP | disclosed |
| US-20030060590-A1 | Producing a low dielectric constant polymer from a thermosetting monomer that has a cage compound or aryl core structure, which is covalently bound to a plurality of arms that contain acetylenic groups | HONEYWELL INTERNATIONAL INC. | 2003-03-27 | — | — | US | disclosed |
| WO-2003007337-A2 | LOW DIELECTRIC CONSTANT ORGANIC DIELECTRICS BASED ON CAGE-LIKE STRUCTURES | HONEYWELL INTERNATIONAL INC. (US) | 2003-01-23 | — | — | WO | disclosed |
| US-6509415-B1 | Crosslinked polyphenylene ethers with cage compounds attached; integrated circuits | HONEYWELL INTERNATIONAL INC. | 2003-01-21 | — | — | US | disclosed |
| EP-1274755-A2 | LOW DIELECTRIC CONSTANT ORGANIC DIELECTRICS BASED ON CAGE-LIKE STRUCTURES | Honeywell International Inc. (US) | 2003-01-15 | — | — | EP | disclosed |
| US-6469123-B1 | THERMOSETTING MONOMER IS INCORPORATED INTO A POLYMER TO FORM THE LOW DIELECTRIC CONSTANT POLYMER; CAGE COMPOUNDS AND CORE STRUCTURES INCLUDE ADAMANTANE, DIAMANTANE, SILICON, A PHENYL GROUP AND A SEXIPHENYLENE | HONEYWELL INTERNATIONAL INC. | 2002-10-22 | — | — | US | disclosed |
| US-20020022708-A1 | Compositions and methods for thermosetting molecules in organic compositions | HONEYWELL INTERNATIONAL INC. | 2002-02-21 | — | — | US | disclosed |
| US-20020016414-A1 | Low dielectric constant organic dielectrics based on cage-like structures | HONEYWELL INTERNATIONAL INC. | 2002-02-07 | — | — | US | disclosed |
| WO-2002008308-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2002-01-31 | — | — | WO | disclosed |
| WO-2001078110-A2 | LOW DIELECTRIC CONSTANT ORGANIC DIELECTRICS BASED ON CAGE-LIKE STRUCTURES | HONEYWELL INTERNATIONAL INC. (US) | 2001-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100008864-A1 | AROMATIC MULTIMERS | AHR, ARG2, PAH | LMNA 3117/4885SLC22A2 810/4885SLC22A1 994/4885 |
| US-20060063834-A1 | Substituted adamantanes, and methods of making the same | DDO, SLC18A2, BACE1 | LMNA 2023/4885SLC22A2 2354/4885SLC22A1 2461/4885 |
| US-20110200536-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | TSPO, PML, AIP | LMNA 4069/4885SLC22A2 900/4885SLC22A1 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.