Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FRK | P42685 | 1/20 | 0.42 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.42 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22719922 | 0.90 | FRK (0.40) | FRKCAMK2BCAMK2GCAMK2DALDH1A1 | |
| SCHEMBL22719950 | 0.86 | MAOB (0.39) | ALDH1A1MAPK1KMT2AMAPT | |
| SCHEMBL22738228 | 0.86 | TRPV1 (0.39) | FRKCAMK2BCAMK2GCAMK2D | |
| SCHEMBL22719951 | 0.82 | INSR (0.45) | ALDH1A1MAPK1KMT2AMAPTSRC | |
| SCHEMBL12398991 | 0.80 | KMT2A (0.48) | ALDH1A1MAPK1KMT2AMAPT | |
| SCHEMBL1503150 | 0.79 | KMT2A (0.47) | ALDH1A1MAPK1KMT2AMAPT | |
| SCHEMBL2147314 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPK1KMT2AMAPT | |
| SCHEMBL1503245 | 0.76 | KMT2A (0.43) | ALDH1A1MAPK1KMT2AHDAC1MAPT | |
| SCHEMBL30193078 | 0.75 | KMT2A (0.40) | ALDH1A1MAPK1KMT2AMAPTGAA | |
| SCHEMBL22719914 | 0.74 | KMT2A (0.43) | ALDH1A1MAPK1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020237374-A1 | PICOLINIC ACID DERIVATIVES AND USE THEREOF FOR TREATING DISEASES ASSOCIATED WITH ELEVATED CHOLESTEROL | MONTREAL HEART INSTITUTE (CA) | 2020-12-03 | — | — | WO | disclosed |
| WO-2020237374-A1 | PICOLINIC ACID DERIVATIVES AND USE THEREOF FOR TREATING DISEASES ASSOCIATED WITH ELEVATED CHOLESTEROL | MONTREAL HEART INSTITUTE (CA) | 2020-12-03 | — | — | WO | disclosed |