Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FRK | P42685 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.37 |
| ▸ | GCGR | P47871 | 4/20 | 0.36 |
| ▸ | ASPH | Q12797 | 2/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22719906 | 0.73 | FRK (0.42) | FRKCAMK2BCAMK2GCAMK2DFFAR1 | |
| SCHEMBL22719922 | 0.72 | FRK (0.40) | FRKCAMK2BCAMK2GCAMK2DFFAR1 | |
| SCHEMBL22738228 | 0.72 | TRPV1 (0.39) | FRKCAMK2BCAMK2GCAMK2D | |
| SCHEMBL22719950 | 0.61 | MAOB (0.39) | — | |
| SCHEMBL16211464 | 0.59 | EPHX2 (0.57) | FRKCAMK2BCAMK2GCAMK2DFFAR1 | |
| SCHEMBL20236549 | 0.59 | FFAR1 (0.69) | FFAR1ASPHKDM8PTGDR2PPARA | |
| SCHEMBL29806160 | 0.58 | DHODH (0.44) | — | |
| SCHEMBL22932198 | 0.58 | DHODH (0.44) | — | |
| Acetic Acid SCHEMBL29202236 | 0.58 | EPHX2 (0.52) | FFAR1 | |
| SCHEMBL951015 | 0.57 | FFAR1 (0.58) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020237374-A1 | PICOLINIC ACID DERIVATIVES AND USE THEREOF FOR TREATING DISEASES ASSOCIATED WITH ELEVATED CHOLESTEROL | MONTREAL HEART INSTITUTE (CA) | 2020-12-03 | — | — | WO | disclosed |