SCHEMBL951015

SCHEMBL951015

O=C(O)CNc1ccc(C(F)(F)F)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.58
EPHX2 P34913 3/20 0.55
L3MBTL1 Q9Y468 1/20 0.53
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA7 P43166 1/20 0.49
KIF11 P52732 1/20 0.47
PTPN1 P18031 1/20 0.47
TGM2 P21980 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ALDH1A1 P00352 1/20 0.47
POLB P06746 1/20 0.47
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5958669 0.85 FFAR1 (0.44) FFAR1EPHX2L3MBTL1NPC1RAB9A
SCHEMBL13760549 0.84 SMN1; SMN2 (0.56) FFAR1
SCHEMBL5692310 0.83 ALDH1A1 (0.44) FFAR1NPC1RAB9ACA12CA1
SCHEMBL24279571 0.83 KIF11 (0.54) FFAR1EPHX2NPC1RAB9ACA12
SCHEMBL18282719 0.83 EPHX2 (0.53) FFAR1EPHX2L3MBTL1NPC1RAB9A
SCHEMBL12156937 0.83 FFAR1 (0.65) FFAR1EPHX2L3MBTL1NPC1RAB9A
Hydrochloric Acid SCHEMBL5773679 0.82 POLB (0.49) FFAR1EPHX2L3MBTL1NPC1RAB9A
SCHEMBL19707556 0.81 RAB9A (0.61) FFAR1EPHX2L3MBTL1NPC1RAB9A
SCHEMBL1441279 0.81 LMNA (0.57) ALDH1A1LMNA
SCHEMBL130789 0.81 SMN1; SMN2 (0.53) EPHX2NPC1RAB9ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118910628-A Selenizing and amination method of olefin under mild electrochemical condition 湘潭大学 2024-11-08 CN claimed
CN-119219546-B Halogenated fullerene pyrrolidine derivative, and preparation method and application thereof XIAMEN UNIVERSITY (CN) 2026-05-26 CN disclosed
WO-2025224599-A1 PYRROLIDINE-BASED GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF PFIZER INC. (US) 2025-10-30 WO disclosed
US-20250326741-A1 GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF PFIZER INC. (US) 2025-10-23 US disclosed
US-12268683-B2 Compounds and methods for synergistic activation of M channels THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-04-08 US disclosed
CN-116554050-B Amide phenol derivative and application thereof 四川大学 2025-03-18 CN disclosed
CN-119219546-A Halogenated fullerene pyrrolidine derivative, and preparation method and application thereof 厦门大学 2024-12-31 CN disclosed
CN-118910628-A Selenizing and amination method of olefin under mild electrochemical condition 湘潭大学 2024-11-08 CN disclosed
WO-2024130161-A2 NOVEL CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF BIONECURE THERAPEUTICS INC (US) 2024-06-20 WO disclosed
US-20240034753-A1 THERAPEUTIC PEPTIDES COHBAR, INC. 2024-02-01 US disclosed
EP-1307214-A1 HIGHLY HOMOGENEOUS MOLECULAR MARKERS FOR ELECTROPHORESIS INVITROGEN CORPORATION (US) 2003-05-07 EP disclosed
EP-1076563-A4 DIPEPTIDE CASPASE INHIBITORS AND THE USE THEREOF CYTOVIA INC (US) 2003-04-23 EP disclosed
US-20020155455-A1 Highly homogeneous molecular markers for electrophoresis INVITROGEN CORPORATION 2002-10-24 US disclosed
EP-1220869-A1 CASPASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF CHEMOTHERAPY AND RADIATION THERAPY INDUCED CELL DEATH Cytovia, Inc. (US) 2002-07-10 EP disclosed
WO-2002013848-A1 HIGHLY HOMOGENEOUS MOLECULAR MARKERS FOR ELECTROPHORESIS INVITROGEN CORPORATION (US) 2002-02-21 WO disclosed
CN-1297354-A Dipeptide caspase inhibitors and use thereof CYTOVIA INC (US) 2001-05-30 CN disclosed
WO-2001027140-A1 CASPASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF CHEMOTHERAPY AND RADIATION THERAPY INDUCED CELL DEATH CYTOVIA, INC. (US) 2001-04-19 WO disclosed
EP-1076563-A1 DIPEPTIDE CASPASE INHIBITORS AND THE USE THEREOF Cytovia, Inc. (US) 2001-02-21 EP disclosed
US-6153591-A PROTECTING NERVOUS SYSTEM FOLLOWING FOCAL ISCHEMIA AND GLOBAL ISCHEMIA; ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, PRION DISEASES, PARKINSON'S DISEASE, MULTIPLE SCLEROSIS, AMYOTROPHIC LATERAL SCLEROSIS, ALOPACIA, RHEUMATOID ARTHRITIS CYTOVIA, INC. (US) 2000-11-28 US disclosed
WO-1999047154-A1 DIPEPTIDE CASPASE INHIBITORS AND THE USE THEREOF CYTOVIA, INC. (US) 1999-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020155455-A1 Highly homogeneous molecular markers for electrophoresis CD44, HLA-C, HLA-A FFAR1 4879/4885EPHX2 334/4885L3MBTL1 3795/4885
US-20250326741-A1 GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF GIPR, GLP1R, GPR119 FFAR1 73/4885EPHX2 4731/4885L3MBTL1 1274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.