Ethyl Acetate

Ethyl Acetate

SCHEMBL22719918

CCOC(C)=O.NNC(=O)CCCCC(=O)NN

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
LMNA P02545 1/20 0.56
HSD17B10 Q99714 1/20 0.56
CTSD P07339 1/20 0.50
GAA P10253 3/20 0.47
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.40
KDM5C P41229 1/20 0.40
PHF8 Q9UPP1 1/20 0.40
KDM2A Q9Y2K7 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38
ALOX15 P16050 1/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
POLB P06746 1/20 0.38
TSHR P16473 1/20 0.38
SMYD3 Q9H7B4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL21877936 0.84 ALOX15 (0.60) ALDH1A1CTSDGAAKMT2AKDM4E
Ethyl Acetate SCHEMBL28130751 0.81 ALDH1A1 (0.70) ALDH1A1LMNAHSD17B10CTSDGAA
Acetone SCHEMBL22554792 0.80 CTSD (0.59) ALDH1A1LMNACTSDGAAKMT2A
Acetone SCHEMBL6392906 0.80 CTSD (0.59) ALDH1A1LMNACTSDGAAKMT2A
SCHEMBL5382123 0.80 CYP1A2 (0.59) ALDH1A1HSD17B10CTSDGAAKMT2A
Acetic Acid SCHEMBL6534753 0.78 CTSD (0.56) ALDH1A1CTSDGAAKDM4EKDM5C
SCHEMBL5606148 0.78 CTSD (0.56) ALDH1A1LMNACTSDGAAKMT2A
SCHEMBL49856 0.78 ALDH1A1 (0.62) ALDH1A1LMNACTSDGAAKDM4E
SCHEMBL4148560 0.77 CTSD (0.50) ALDH1A1LMNAHSD17B10CTSDGAA
SCHEMBL21877937 0.77 CTSD (0.42) ALDH1A1LMNACTSDGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3976580-A1 PRECURSOR COMPOUNDS OF ESTER COMPOUNDS University of Guelph (CA) 2022-04-06 EP disclosed
WO-2020237378-A1 PRECURSOR COMPOUNDS OF ESTER COMPOUNDS UNIVERSITY OF GUELPH (CA) 2020-12-03 WO disclosed