Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HPGDS | O60760 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12435559 | 0.99 | RAB9A (0.60) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL13161912 | 0.88 | HPGDS (0.56) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL1580074 | 0.86 | MAPK1 (0.56) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL1579576 | 0.84 | GAA (0.48) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL787120 | 0.83 | RAB9A (0.58) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL3455875 | 0.83 | ALDH1A1 (0.70) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28684615 | 0.83 | RAB9A (0.61) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11239859 | 0.83 | ALDH1A1 (0.70) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL22720107 | 0.81 | RAB9A (0.68) | RAB9AALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL22720141 | 0.80 | NPC1 (0.70) | RAB9AALDH1A1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239050-A1 | 2-(2-CHLORO-4-METHYLPHENYL)QUINAZOLINE-4(3H)-KETONE COMPOUND AND MEDICAL USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2020-12-03 | — | — | WO | disclosed |
| CN-110041273-B | 2- (2-chloro-4-methylphenyl) quinazoline-4 (3H) -ketone compound and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-20 | — | — | CN | disclosed |