Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22720302 | 0.86 | FPR2 (0.40) | MAPTALDH1A1FPR2MEN1KMT2A | |
| SCHEMBL22720334 | 0.83 | FPR2 (0.46) | MAPTALDH1A1FPR2MEN1KMT2A | |
| SCHEMBL22720220 | 0.78 | USP30 (0.40) | MAPTALDH1A1FPR2MEN1KMT2A | |
| SCHEMBL23422324 | 0.78 | USP30 (0.47) | MAPTALDH1A1FPR2MEN1KMT2A | |
| SCHEMBL14815454 | 0.78 | USP30 (0.47) | MAPTALDH1A1FPR2MEN1KMT2A | |
| SCHEMBL31027198 | 0.78 | USP30 (0.47) | MAPTALDH1A1FPR2MEN1KMT2A | |
| SCHEMBL16763628 | 0.76 | FPR2 (0.52) | MAPTALDH1A1FPR2MEN1KMT2A | |
| SCHEMBL27175858 | 0.76 | FPR2 (0.52) | MAPTALDH1A1FPR2MEN1KMT2A | |
| SCHEMBL16763626 | 0.76 | FPR2 (0.52) | MAPTALDH1A1FPR2MEN1KMT2A | |
| SCHEMBL22720343 | 0.76 | USP30 (0.41) | MAPTALDH1A1FPR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |