Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22720281 | 0.86 | FPR2 (0.39) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL31027198 | 0.78 | USP30 (0.47) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14815454 | 0.78 | USP30 (0.47) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL23422324 | 0.78 | USP30 (0.47) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22720335 | 0.78 | MAPT (0.42) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17188206 | 0.74 | USP30 (0.46) | USP30MAPTFPR2KDM4ETHRB | |
| SCHEMBL31257362 | 0.74 | USP30 (0.46) | USP30MAPTFPR2KDM4ETHRB | |
| SCHEMBL22720343 | 0.74 | USP30 (0.41) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22720334 | 0.74 | FPR2 (0.46) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29586410 | 0.72 | MAPT (0.46) | USP30MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |