Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22720311 | 0.88 | FPR2 (0.42) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28704461 | 0.85 | ALDH1A1 (0.37) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22720341 | 0.84 | USP30 (0.45) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22720335 | 0.76 | MAPT (0.42) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL31257370 | 0.74 | USP30 (0.47) | USP30MAPTGPR119FPR2KDM4E | |
| SCHEMBL22720220 | 0.74 | USP30 (0.40) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22720287 | 0.74 | FPR2 (0.39) | MAPTALDH1A1MEN1KMT2AGPR119 | |
| SCHEMBL23422324 | 0.73 | USP30 (0.47) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL31027198 | 0.73 | USP30 (0.47) | USP30MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14815454 | 0.73 | USP30 (0.47) | USP30MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113396147-B | Aromatic heterocyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113396147-A | Aromatic heterocyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-09-14 | — | — | CN | disclosed |
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |