Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31124564 | 1.00 | CRHR1 (0.31) | CRHR1 | |
| SCHEMBL31124565 | 1.00 | CRHR1 (0.31) | CRHR1 | |
| SCHEMBL31124584 | 0.80 | NOS3 (0.36) | CRHR1 | |
| SCHEMBL22720397 | 0.80 | NOS3 (0.36) | CRHR1 | |
| SCHEMBL23234577 | 0.76 | GABRA1 (0.33) | — | |
| SCHEMBL21544179 | 0.76 | CYP3A4 (0.34) | — | |
| SCHEMBL22720418 | 0.67 | CA12 (0.33) | — | |
| SCHEMBL29572355 | 0.67 | CA12 (0.33) | — | |
| SCHEMBL21543450 | 0.65 | — | — | |
| SCHEMBL25946320 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239077-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |
| WO-2020239077-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |