Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 6/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20665382 | 0.80 | MEN1 (0.43) | MEN1KMT2ACHRNB4CHRNA3KCNH2 | |
| SCHEMBL22720477 | 0.75 | MEN1 (0.39) | MEN1KMT2APARP1CHRNB4CHRNA3 | |
| SCHEMBL22720412 | 0.74 | PARP1 (0.42) | PARP1CHRNB4CHRNA3GSK3BPARP2 | |
| SCHEMBL5957154 | 0.72 | HCRTR1 (0.41) | LMNAGSK3B | |
| SCHEMBL6645725 | 0.70 | PARP1 (0.45) | PARP1PARP2CREBBP | |
| SCHEMBL5737272 | 0.68 | ALDH1A1 (0.45) | LMNA | |
| SCHEMBL9461761 | 0.67 | PARP1 (0.46) | MEN1KMT2APARP1IRAK4PARP2 | |
| SCHEMBL6646332 | 0.67 | PARP1 (0.41) | MEN1KMT2APARP1IRAK4PARP2 | |
| SCHEMBL28672144 | 0.65 | MEN1 (0.45) | MEN1KMT2AKCNH2 | |
| SCHEMBL9335076 | 0.64 | MEN1 (0.46) | MEN1KMT2APARP1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |