Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 9/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22720476 | 0.75 | MEN1 (0.39) | MEN1KMT2APARP1PARP2CREBBP | |
| SCHEMBL22720416 | 0.74 | PARP1 (0.40) | PARP1PARP2 | |
| SCHEMBL30103427 | 0.69 | PLAU (0.43) | — | |
| SCHEMBL22638941 | 0.66 | MEN1 (0.44) | MEN1KMT2APDCD1LG2CD274CHRNB4 | |
| SCHEMBL28697920 | 0.66 | MEN1 (0.44) | MEN1KMT2APDCD1LG2CD274CHRNB4 | |
| SCHEMBL38665739 | 0.64 | PLAU (0.36) | LMNA | |
| SCHEMBL9335076 | 0.64 | MEN1 (0.46) | MEN1KMT2APARP1CHRNB4CHRNA3 | |
| Proline SCHEMBL9616967 | 0.64 | KDM4E (0.39) | MEN1KMT2A | |
| SCHEMBL10002365 | 0.63 | MEN1 (0.39) | MEN1KMT2APARP1 | |
| SCHEMBL28944768 | 0.62 | PARP1 (0.54) | PARP1PARP2PARP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |