Fluorene

Fluorene

SCHEMBL22720649

c1ccc(CCc2ccccc2)cc1.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
MAPT P10636 3/20 0.51
RAB9A P51151 2/20 0.51
APAF1 O14727 2/20 0.51
KMT2A Q03164 2/20 0.51
CASP1 P29466 2/20 0.51
HSD17B10 Q99714 2/20 0.51
GAA P10253 1/20 0.51
BLM P54132 1/20 0.51
CASP7 P55210 1/20 0.51
MAOA P21397 3/20 0.50
HPGD P15428 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
LMNA P02545 1/20 0.47
MEN1 O00255 1/20 0.46
SRD5A2 P31213 1/20 0.46
FFAR1 O14842 1/20 0.45
MAOB P27338 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL14118022 0.84 MAOA (0.65) ALDH1A1MAPTRAB9AKMT2AHSD17B10
Fluorene SCHEMBL28818074 0.82 MAOA (0.62) ALDH1A1MAPTRAB9AKMT2AHSD17B10
Fluorene SCHEMBL29478468 0.82 MAOA (0.68) ALDH1A1MAPTRAB9AKMT2AHSD17B10
Fluorene SCHEMBL545861 0.82 MAOA (0.68) ALDH1A1MAPTRAB9AKMT2AHSD17B10
Fluorene SCHEMBL8180 0.82 MAOA (0.68) ALDH1A1MAPTRAB9AKMT2AHSD17B10
Fluorene SCHEMBL29355380 0.82 MAOA (0.68) ALDH1A1MAPTRAB9AKMT2AHSD17B10
Fluorene SCHEMBL31388525 0.82 MAOA (0.68) ALDH1A1MAPTRAB9AKMT2AHSD17B10
SCHEMBL7195015 0.80 GPR84 (0.60) ALDH1A1MAPTRAB9AHSD17B10MAOA
SCHEMBL7190397 0.80 GPR84 (0.52) ALDH1A1MAPTRAB9AHSD17B10MAOA
SCHEMBL8910238 0.80 GPR84 (0.49) ALDH1A1MAPTRAB9AMAOAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112851547-B Fluorene oxime ester compound, preparation method thereof and photosensitive resin composition 常州强力先端电子材料有限公司 2024-06-07 CN disclosed
CN-112851547-B Fluorene oxime ester compound, preparation method thereof and photosensitive resin composition 常州强力先端电子材料有限公司 2024-06-07 CN disclosed
CN-112409295-B Fluorene initiator, photocuring composition containing same and application thereof 常州强力先端电子材料有限公司 2023-04-07 CN disclosed
CN-112851547-A Fluorenoxime ester compound, preparation method thereof and photosensitive resin composition 常州强力先端电子材料有限公司 2021-05-28 CN disclosed
CN-112851547-A Fluorenoxime ester compound, preparation method thereof and photosensitive resin composition 常州强力先端电子材料有限公司 2021-05-28 CN disclosed
CN-112409295-A Fluorene initiator, photocuring composition containing same and application thereof 常州强力先端电子材料有限公司 2021-02-26 CN disclosed
WO-2020238862-A1 FLUORENE INITIATOR, PHOTOCURABLE COMPOSITION COMPRISING SAME, AND APPLICATION THEREOF 常州强力先端电子材料有限公司 2020-12-03 WO disclosed