Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2269781 | 0.84 | SIGMAR1 (0.37) | TSHRSIGMAR1 | |
| SCHEMBL20637313 | 0.81 | TSHR (0.41) | TSHRCHRM2ADRA1ACYP3A4CYP2D6 | |
| SCHEMBL2266535 | 0.78 | TSHR (0.38) | TSHRHKDC1 | |
| SCHEMBL2272377 | 0.75 | TSHR (0.36) | TSHRCYP2C9KMT2AMEN1MAPT | |
| SCHEMBL2270937 | 0.74 | TSHR (0.35) | TSHRCHRM2ADRA1ACYP2D6ALOX15 | |
| SCHEMBL15915010 | 0.72 | TSHR (0.59) | TSHRKDM4EALDH1A1 | |
| SCHEMBL2267939 | 0.72 | HTR2A (0.44) | TSHRCHRM2ADRA1ACYP3A4CYP2D6 | |
| SCHEMBL3316317 | 0.70 | TSHR (0.40) | TSHRGLALMNAMAPTALDH1A1 | |
| SCHEMBL235044 | 0.70 | TSHR (0.35) | TSHRCHRM2ADRA1ACYP3A4CYP2D6 | |
| SCHEMBL2273792 | 0.68 | TAAR1 (0.52) | TSHRCYP3A4CYP2D6ALOX15ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404584-B2 | Method of manufacturing semiconductor device | FUJITSU LIMITED (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20110207319-A1 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE | FUJITSU LIMITED (JP) | 2011-08-25 | — | — | US | disclosed |