SCHEMBL2266535

SCHEMBL2266535

CCC(c1ccccc1[SiH3])C(C)Cl

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
HKDC1 Q2TB90 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20637313 0.84 TSHR (0.41) TSHRHKDC1
SCHEMBL2272199 0.78 TSHR (0.36) TSHRHKDC1
SCHEMBL2272377 0.78 TSHR (0.36) TSHR
SCHEMBL10717115 0.78 TSHR (0.38) TSHR
SCHEMBL10318391 0.77 TSHR (0.38) TSHR
SCHEMBL2270937 0.77 TSHR (0.35) TSHR
SCHEMBL2269781 0.77 SIGMAR1 (0.37) TSHR
SCHEMBL15915010 0.75 TSHR (0.59) TSHR
SCHEMBL68911 0.74 GABRA1 (0.36) TSHR
SCHEMBL3316317 0.73 TSHR (0.40) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed