SCHEMBL2272256

SCHEMBL2272256

CCC(C)[SiH](NC)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.35
SIGMAR1 Q99720 3/20 0.35
SLC18A2 Q05940 1/20 0.35
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KCNN4 O15554 2/20 0.32
TRPA1 O75762 1/20 0.32
HRH1 P35367 2/20 0.32
CACNA1F O60840 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
ADRA2B P18089 1/20 0.32
CHRM3 P20309 1/20 0.32
ADRA1A P35348 1/20 0.32
OPRK1 P41145 1/20 0.32
CACNA1D Q01668 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268681 0.82 TSHR (0.38) TAAR1SIGMAR1SLC18A2CYP3A4LMNA
SCHEMBL2270888 0.79 TDP1 (0.36) TAAR1SIGMAR1SLC18A2KDM4ECYP3A4
SCHEMBL15914960 0.79 LMNA (0.38) TAAR1SIGMAR1SLC18A2CYP3A4LMNA
SCHEMBL2101840 0.77 SIGMAR1 (0.33) TAAR1SIGMAR1KCNN4TSHR
SCHEMBL2104329 0.75 CACNA2D1 (0.38) SIGMAR1KDM4ECYP3A4MEN1KMT2A
SCHEMBL15915020 0.74 LMNA (0.38) TAAR1SIGMAR1LMNAMEN1KMT2A
SCHEMBL10454800 0.71 TSHR (0.38) TAAR1SIGMAR1KDM4ELMNAMEN1
SCHEMBL2269772 0.71 LMNA (0.35) TAAR1SIGMAR1LMNAMEN1KMT2A
SCHEMBL12815012 0.69 LMNA (0.34) TAAR1SIGMAR1LMNAMEN1KMT2A
SCHEMBL15915272 0.69 LMNA (0.34) TAAR1SIGMAR1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed