SCHEMBL22723014

SCHEMBL22723014

COCC(C)OCC(C)OC=C(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TBXAS1 P24557 1/20 0.34
LMNA P02545 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.33
AKT1 P31749 1/20 0.33
TSHR P16473 1/20 0.33
HPGD P15428 3/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP2D6 P10635 1/20 0.31
POLB P06746 1/20 0.31
XBP1 P17861 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22723010 0.94 KMT2A (0.40) MEN1KMT2ATBXAS1LMNAALDH1A1
SCHEMBL28696242 0.87 MEN1 (0.36) MEN1KMT2ALMNAALDH1A1MAPT
SCHEMBL28736961 0.85 CES2 (0.45) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL22753319 0.85 CES2 (0.45) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL28736959 0.85 CES2 (0.45) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL29445797 0.80 KMT2A (0.40) MEN1KMT2ALMNAALDH1A1MAPT
SCHEMBL23082958 0.79 HPGD (0.35) MEN1KMT2AALDH1A1HPGD
SCHEMBL29489768 0.79 HPGD (0.35) MEN1KMT2AALDH1A1HPGD
SCHEMBL23082942 0.79 HPGD (0.35) MEN1KMT2AALDH1A1HPGD
SCHEMBL29571256 0.79 HPGD (0.35) MEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518899-B2 Aromatic enol ether paint additives EASTMAN CHEMICAL COMPANY (US) 2022-12-06 US disclosed
US-11518899-B2 Aromatic enol ether paint additives EASTMAN CHEMICAL COMPANY (US) 2022-12-06 US disclosed
EP-4025657-A1 AROMATIC ENOL ETHER PAINT ADDITIVES Eastman Chemical Company (US) 2022-07-13 EP disclosed
EP-4025558-A1 AROMATIC ENOL ETHERS Eastman Chemical Company (US) 2022-07-13 EP disclosed
WO-2022076359-A1 A PROCESS FOR MAKING ENOL ETHERS EASTMAN CHEMICAL COMPANY (US) 2022-04-14 WO disclosed
WO-2021046006-A1 AROMATIC ENOL ETHERS EASTMAN CHEMICAL COMPANY (US) 2021-03-11 WO disclosed
WO-2021046040-A1 AROMATIC ENOL ETHER PAINT ADDITIVES EASTMAN CHEMICAL COMPANY (US) 2021-03-11 WO disclosed
US-20210062031-A1 AROMATIC ENOL ETHER PAINT ADDITIVES EASTMAN CHEMICAL COMPANY (US) 2021-03-04 US disclosed
US-20210062031-A1 AROMATIC ENOL ETHER PAINT ADDITIVES EASTMAN CHEMICAL COMPANY (US) 2021-03-04 US disclosed
US-10858304-B1 Aromatic enol ethers EASTMAN CHEMICAL COMPANY (US) 2020-12-08 US disclosed
US-10858304-B1 Aromatic enol ethers EASTMAN CHEMICAL COMPANY (US) 2020-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10858304-B1 Aromatic enol ethers ETV1, ENO1, MYB MEN1 3832/4885KMT2A 1705/4885TBXAS1 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.