SCHEMBL227249

SCHEMBL227249

CCCCCCCCOc1ccccc1-c1cc(-c2ccc(N(C)C)cc2)cc(-c2ccccc2)n1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 12/20 0.59
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
PTPN11 Q06124 1/20 0.44
TLR8 Q9NR97 2/20 0.43
ADK P55263 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
PDE5A O76074 1/20 0.40
PDE4A P27815 1/20 0.40
PDE4B Q07343 1/20 0.40
PDE4C Q08493 1/20 0.40
PDE4D Q08499 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17255090 1.00 LTB4R (0.59) LTB4RTHRATHRBPTPN11TLR8
SCHEMBL29420400 1.00 LTB4R (0.59) LTB4RTHRATHRBPTPN11TLR8
SCHEMBL29430011 1.00 LTB4R (0.59) LTB4RTHRATHRBPTPN11TLR8
SCHEMBL17536604 0.99 LTB4R (0.57) LTB4RTHRATHRBPTPN11TLR8
SCHEMBL29430028 0.96 LTB4R (0.55) LTB4RTLR8ADKMAOAMAOB
SCHEMBL17255105 0.96 LTB4R (0.55) LTB4RTLR8ADKMAOAMAOB
SCHEMBL8621067 0.96 LTB4R (0.52) LTB4RTHRATHRBPTPN11TLR8
SCHEMBL8617052 0.96 LTB4R (0.52) LTB4RTHRATHRBPTPN11TLR8
SCHEMBL8615810 0.96 LTB4R (0.52) LTB4RTHRATHRBPTPN11TLR8
SCHEMBL29429991 0.96 LTB4R (0.52) LTB4RTHRATHRBPTPN11TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4644130-A2 A COMPOSITION DataLase Ltd. (GB) 2025-11-05 EP claimed
US-12139626-B2 Irreversibly erasable ink composition having a discoloration agent SOCIéTé BIC (FR) 2024-11-12 US claimed
US-12043596-B2 Thermochromic pigment compositions SOCIETE BIC (FR) 2024-07-23 US claimed
US-20240182760-A1 A COMPOSITION DATALASE LTD. (GB) 2024-06-06 US claimed
CN-115298270-B Method for preparing thermochromic water-based gel ink composition and thermochromic water-based gel ink composition thereof 法国比克公司 2024-03-26 CN claimed
US-11920047-B2 Method for preparing thermochromic water-based gel ink compositions, and thermochromic water-based gel ink compositions thereof SOCIéTé BIC (FR) 2024-03-05 US claimed
EP-3859211-B1 HANDHELD LIGHTER WITH HIGH TEMPERATURE WARNING INDICATOR SOCIéTé BIC (FR) 2024-01-24 EP claimed
US-20240010020-A1 A COMPOSITION DATALASE LTD. (GB) 2024-01-11 US claimed
US-11814528-B2 Diester of bisphenol fluorene compounds and thermochromic pigment compositions comprising the same SOCIéTé BIC (FR) 2023-11-14 US claimed
US-11787226-B2 Eraser tool containing polyetheramine SOCIETE BIC (FR) 2023-10-17 US claimed
WO-2018197807-A1 NOVEL COMPOUNDS OF FORMULA (I) AND USE THEREOF IN THERMOCHROMIC PIGMENT COMPOSITIONS SOCIETE BIC (FR) 2018-11-01 WO claimed
WO-2018197808-A1 THERMOCHROMIC PIGMENT COMPOSITIONS SOCIETE BIC (FR) 2018-11-01 WO claimed
WO-2018150146-A1 NOVEL THERMOCHROMIC PIGMENT COMPOSITION COMPRISING A COMPOUND OF FORMULA (I) AS REACTION MEDIUM SOCIETE BIC (FR) 2018-08-23 WO claimed
US-9751352-B2 Heat-sensitive recording medium displaying gold metal tone, and/or heat-sensitive recording medium displaying two different color tones Oji Holdings Corporation (JP) 2017-09-05 US claimed
EP-2995466-A1 HEAT-SENSITIVE RECORDING MEDIUM DISPLAYING GOLD METAL TONE, AND/OR HEAT-SENSITIVE RECORDING MEDIUM DISPLAYING TWO DIFFERENT COLOR TONES Oji Holdings Corporation (JP) 2016-03-16 EP claimed
US-20160059604-A1 HEAT-SENSITIVE RECORDING MEDIUM DISPLAYING GOLD METAL TONE, AND/OR HEAT-SENSITIVE RECORDING MEDIUM DISPLAYING TWO DIFFERENT COLOR TONES Oji Holdings Corporation (JP) 2016-03-03 US claimed
EP-2018365-A1 NEW MATERIALS FOR LITHOGRAPHIC PLATES COATINGS, LITHOGRAPHIC PLATES AND COATINGS CONTAINING SAME, METHODS OF PREPARATION AND USE American Dye Source, Inc. (CA) 2009-01-28 EP claimed
WO-2007131336-A1 NEW MATERIALS FOR LITHOGRAPHIC PLATES COATINGS, LITHOGRAPHIC PLATES AND COATINGS CONTAINING SAME, METHODS OF PREPARATION AND USE AMERICAN DYE SOURCE INC. (CA) 2007-11-22 WO claimed
US-6664024-B1 Photopolymerizable epoxide compound, photoinitiator, photoactivated color changer, and reactive polysilsesquioxane compound; colorimetric analysis; stereolithography AMERICAN DYE SOURCE, INC. (CA) 2003-12-16 US claimed
US-5126233-A Oil soluble color precursor involving certain crystalline 6-phenyl pyridine derivatives THE MEAD CORPORATION (US) 1992-06-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043596-B2 Thermochromic pigment compositions TYR, MITF, CRY2 LTB4R 1878/4885THRA 1732/4885THRB 1157/4885
US-11814528-B2 Diester of bisphenol fluorene compounds and thermochromic pigment compositions comprising the same TYR, MITF, RB1 LTB4R 794/4885THRA 1355/4885THRB 1293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.