SCHEMBL22727240

SCHEMBL22727240

Cc1ccc2c(c1)C(=O)c1cc(Cc3ccc4c(c3)C(=O)c3ccccc3C4=O)ccc1S2(=O)=O

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.58
ALDH1A1 P00352 4/20 0.50
NPC1 O15118 2/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CHEK1 O14757 2/20 0.49
MAOA P21397 3/20 0.44
MAOB P27338 1/20 0.44
GPR3 P46089 1/20 0.41
KDM4E B2RXH2 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11635548 0.82 ELANE (0.58) ELANEALDH1A1NPC1MAPK1L3MBTL1
SCHEMBL18267540 0.80 ELANE (0.52) ELANEALDH1A1MAOAMAOBGPR3
Tectoquinone SCHEMBL5089866 0.77 MAPT (0.83) ELANEALDH1A1NPC1LMNAMAPT
SCHEMBL20389945 0.77 MAOA (0.59) ELANEL3MBTL1CHEK1MAOAMAOB
SCHEMBL13421899 0.77 GPR3 (0.64) ELANEALDH1A1LMNACHEK1MAOA
Tectoquinone SCHEMBL2444159 0.76 ELANE (1.00) ELANEALDH1A1NPC1LMNAMAPT
Tectoquinone SCHEMBL36822 0.76 ELANE (1.00) ELANEALDH1A1NPC1LMNAMAPT
Tectoquinone SCHEMBL29403487 0.76 ELANE (1.00) ELANEALDH1A1NPC1LMNAMAPT
Tectoquinone SCHEMBL30618448 0.76 ELANE (1.00) ELANEALDH1A1NPC1LMNAMAPT
Tectoquinone SCHEMBL28051910 0.76 ELANE (1.00) ELANEALDH1A1NPC1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11552254-B2 Thermally activated delayed fluorescent molecular material, a synthesizing method therefor, and an electroluminescent device WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-01-10 US disclosed
US-20200381632-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MOLECULAR MATERIAL, A SYNTHESIZING METHOD THEREFOR, AND AN ELECTROLUMINESCENT DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11552254-B2 Thermally activated delayed fluorescent molecular material, a synthesizing method therefor, and an electroluminescent device FARSB, WEE1, WASF2 ELANE 4814/4885ALDH1A1 1783/4885NPC1 4475/4885
US-20200381632-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MOLECULAR MATERIAL, A SYNTHESIZING METHOD THEREFOR, AND AN ELECTROLUMINESCENT DEVICE FARSB, WEE1, WASF2 ELANE 4814/4885ALDH1A1 1783/4885NPC1 4475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.