SCHEMBL2272809

SCHEMBL2272809

CCN[SiH2]CCC(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 8/20 0.47
HTR2A P28223 7/20 0.47
KCNH2 Q12809 4/20 0.43
CYP3A4 P08684 2/20 0.43
HTR1A P08908 2/20 0.43
ADORA3 P0DMS8 2/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
ADRA1A P35348 2/20 0.43
OPRM1 P35372 2/20 0.43
DRD3 P35462 2/20 0.43
SLC6A3 Q01959 2/20 0.43
LMNA P02545 2/20 0.43
CHRM2 P08172 1/20 0.43
ADRA2A P08913 1/20 0.43
CHRM1 P11229 1/20 0.43
SMPD1 P17405 1/20 0.43
DRD1 P21728 1/20 0.43
TBXA2R P21731 1/20 0.43
CASR P41180 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2272197 0.80 HRH1 (0.55) HRH1HTR2AKCNH2CYP3A4HTR1A
SCHEMBL107889 0.74 HRH1 (0.56) HRH1HTR2AKCNH2CYP3A4HTR1A
Diethylamine SCHEMBL11102663 0.74 HRH1 (0.52) HRH1HTR2AKCNH2CYP3A4HTR1A
SCHEMBL707328 0.73 HRH1 (0.50) HRH1HTR2AKCNH2CYP3A4HTR1A
Hydrochloric Acid SCHEMBL6521685 0.72 HRH1 (0.54) HRH1HTR2AKCNH2CYP3A4HTR1A
SCHEMBL28229621 0.72 HRH1 (0.54) HRH1HTR2AKCNH2CYP3A4HTR1A
Hydrogen Peroxide SCHEMBL27864054 0.72 HRH1 (0.54) HRH1HTR2AKCNH2CYP3A4HTR1A
Ammonia Solution, Strong SCHEMBL5724927 0.72 HRH1 (0.54) HRH1HTR2AKCNH2CYP3A4HTR1A
Ethylene SCHEMBL28169737 0.70 HRH1 (0.52) HRH1HTR2AKCNH2CYP3A4HTR1A
SCHEMBL5999515 0.69 HRH1 (0.63) HRH1HTR2AKCNH2CYP3A4HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed