Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13308398 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1GAAHTT | |
| SCHEMBL3151260 | 0.98 | ALDH1A1 (0.38) | ALDH1A1MAPTMEN1GAAHTT | |
| SCHEMBL3170271 | 0.91 | GRIA2 (0.38) | ALDH1A1MAPTMEN1GAAHTT | |
| SCHEMBL2796832 | 0.83 | SLC6A2 (0.39) | ALDH1A1MAPTMEN1GAAHTT | |
| SCHEMBL14278988 | 0.82 | FPR2 (0.38) | ALDH1A1MAPTKMT2ANAAAIDO1 | |
| SCHEMBL9142389 | 0.81 | KDM1A (0.45) | ALDH1A1MAPTMEN1HTTKMT2A | |
| SCHEMBL13067140 | 0.81 | KDM1A (0.45) | ALDH1A1MAPTMEN1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL4635148 | 0.81 | SLC6A2 (0.38) | ALDH1A1MAPTMEN1GAAHTT | |
| SCHEMBL9144057 | 0.80 | ESR1 (0.35) | ALDH1A1HSD11B1 | |
| SCHEMBL9143256 | 0.79 | KDM1A (0.46) | ALDH1A1MAPTMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243027-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SAGE THERAPEUTICS, INC. (US) | 2020-12-03 | — | — | WO | disclosed |