Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21224595 | 0.81 | ALDH1A1 (0.33) | MAPTMAPK1PNMTADRA2ASIGMAR1 | |
| SCHEMBL20850849 | 0.75 | HRH3 (0.45) | NPC1MAPTSIGMAR1ALDH1A1TDP1 | |
| SCHEMBL3355193 | 0.73 | MAPT (0.49) | NOTUMNPC1MAPTMAPK1RAB9A | |
| SCHEMBL30168551 | 0.73 | MAPT (0.49) | NOTUMNPC1MAPTMAPK1RAB9A | |
| SCHEMBL28239511 | 0.73 | MAPT (0.49) | NPC1MAPTMAPK1RAB9APNMT | |
| SCHEMBL15524921 | 0.72 | DRD4 (0.47) | NPC1MAPTMAPK1RAB9ASERPINE1 | |
| SCHEMBL5678082 | 0.71 | LMNA (0.53) | NPC1MAPTMAPK1RAB9APNMT | |
| SCHEMBL1867023 | 0.71 | MAPT (0.45) | NPC1MAPTMAPK1RAB9APNMT | |
| SCHEMBL18422001 | 0.71 | GRIN2B (0.47) | SIGMAR1ALDH1A1KMT2ADRD4TDP1 | |
| SCHEMBL31036104 | 0.71 | ALDH1A1 (0.47) | MAPTMAPK1PNMTADRA2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392107-A1 | CYCLIC AMINE DERIVATIVE AND MEDICAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2020-12-17 | — | — | US | disclosed |
| US-20200392107-A1 | CYCLIC AMINE DERIVATIVE AND MEDICAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2020-12-17 | — | — | US | disclosed |
| EP-3747879-A1 | CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Toray Industries, Inc. (JP) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392107-A1 | CYCLIC AMINE DERIVATIVE AND MEDICAL USE THEREOF | NPR3, SLC10A1, CNR2 | NOTUM 3685/4885NPC1 609/4885MAPT 3679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.