SCHEMBL22729317

SCHEMBL22729317

COCC(O)CNCCCCCCCCCCCCCCCCCCCCCCCCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28460427 0.81 PABPC1 (0.34) KDM4EALDH1A1KMT2A
SCHEMBL20332566 0.79 SMN1; SMN2 (0.39) HPGDHTTSMN1; SMN2KMT2A
SCHEMBL21691018 0.78 SMN1; SMN2 (0.44) HPGDHTTSMN1; SMN2KMT2A
SCHEMBL1526142 0.78 SMN1; SMN2 (0.35) HPGDHTTSMN1; SMN2KMT2A
SCHEMBL13405585 0.78 ALDH1A1 (0.46) HPGDHTTSMN1; SMN2ALDH1A1KMT2A
SCHEMBL9971264 0.78 ALDH1A1 (0.46) HPGDHTTSMN1; SMN2ALDH1A1KMT2A
SCHEMBL16018106 0.78 ALDH1A1 (0.46) HPGDHTTSMN1; SMN2ALDH1A1KMT2A
SCHEMBL905407 0.77 TSHR (0.47) HPGDHTTSMN1; SMN2ALDH1A1KMT2A
SCHEMBL19463301 0.77 TSHR (0.47) HPGDHTTSMN1; SMN2ALDH1A1KMT2A
SCHEMBL29044559 0.77 TSHR (0.47) HPGDHTTSMN1; SMN2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111770767-B Extracorporeal device and matrix for removing plasmin from biological fluids, method and use thereof 普拉斯富瑞有限公司 2024-03-05 CN disclosed
EP-3746151-A1 EXTRACORPOREAL DEVICE AND MATRIX FOR REMOVING FIBRINOLYTIC PROTEINS FROM BIOLOGICAL FLUIDS, METHODS AND USES THEREOF PLAS-FREE LTD. (IL) 2020-12-09 EP disclosed
CN-111770767-A Extracorporeal device and matrix for the removal of fibrinolytic proteins from biological fluids, method and use thereof 普拉斯富瑞有限公司 2020-10-13 CN disclosed