SCHEMBL28460427

SCHEMBL28460427

COCC(O)CNCCCCCCCCCCCCCCCCCCCCCCCCCC(=O)ON1OCCO1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 1/20 0.34
APOBEC3A P31941 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
KMT2A Q03164 1/20 0.34
PAOX Q6QHF9 1/20 0.33
GLA P06280 1/20 0.33
LMNA P02545 1/20 0.32
NFKB1 P19838 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NR1I2 O75469 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
PTGS2 P35354 1/20 0.32
EPHX2 P34913 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29169675 0.86 KDM4E (0.36) KDM4EALDH1A1KMT2AADRB2
SCHEMBL22729317 0.81 HPGD (0.39) KDM4EALDH1A1KMT2A
SCHEMBL30786011 0.77 ALDH1A1 (0.50) KDM4EALDH1A1KMT2ALMNANFKB1
SCHEMBL23095680 0.77 KDM4E (0.40) KDM4EALDH1A1KMT2APAOXADRB2
SCHEMBL28466832 0.76 KDM4E (0.36) KDM4EALDH1A1KMT2APAOXLMNA
SCHEMBL22729319 0.74 KDM4E (0.39) KDM4EALDH1A1KMT2A
SCHEMBL28466833 0.72 CYP3A4 (0.37) KDM4EALDH1A1KMT2A
SCHEMBL28998884 0.70 ALDH1A1 (0.50) ALDH1A1EPHX2
SCHEMBL22729315 0.70 KDM4E (0.42) KDM4EALDH1A1KMT2AADRB2ADRB1
SCHEMBL29169677 0.70 ALDH1A1 (0.40) KDM4EALDH1A1KMT2AADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111770767-B Extracorporeal device and matrix for removing plasmin from biological fluids, method and use thereof 普拉斯富瑞有限公司 2024-03-05 CN disclosed
CN-111770767-A Extracorporeal device and matrix for the removal of fibrinolytic proteins from biological fluids, method and use thereof 普拉斯富瑞有限公司 2020-10-13 CN disclosed