Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 5/20 | 0.43 |
| ▸ | SCD | O00767 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729812 | 0.92 | CYP2C9 (0.54) | CYP2C9CYP2C19MAPK14HTR2BALDH1A1 | |
| SCHEMBL22729723 | 0.90 | CYP2C9 (0.47) | CYP2C9CYP2C19MAPK14HTR2BALDH1A1 | |
| SCHEMBL22729693 | 0.89 | CYP2C9 (0.61) | CYP2C9CYP2C19MAPK14HTR2BALDH1A1 | |
| SCHEMBL22729710 | 0.85 | ALDH1A1 (0.41) | CYP2C9CYP2C19MAPK14HTR2BALDH1A1 | |
| SCHEMBL22729580 | 0.83 | SPR (0.41) | SCD5SCDALDH1A1HSD17B10KDM4E | |
| SCHEMBL22729463 | 0.83 | SCD (0.41) | SCD5SCDALDH1A1HSD17B10KDM4E | |
| SCHEMBL22729610 | 0.80 | ALDH1A1 (0.41) | CYP2C9CYP2C19MAPK14HTR2BALDH1A1 | |
| SCHEMBL22729683 | 0.79 | SCD5 (0.45) | CYP2C9CYP2C19MAPK14HTR2BSCD5 | |
| SCHEMBL22729854 | 0.79 | GRIN2D (0.46) | CYP2C9CYP2C19MAPK14HTR2BALDH1A1 | |
| SCHEMBL22729535 | 0.78 | ALDH1A1 (0.45) | CYP2C9CYP2C19ALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | CYP2C9 4675/4885CYP2C19 4072/4885MAPK14 1506/4885 |
| US-11459325-B2 | Heterocyclic compound | GBA1, GBA2, GALC | CYP2C9 4642/4885CYP2C19 3977/4885MAPK14 1556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.