Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | TAF1 | P21675 | 1/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729712 | 1.00 | EPHX2 (0.39) | EPHX2ALDH1A1FAAHCNR1CNR2 | |
| SCHEMBL22729639 | 0.89 | ALDH1A1 (0.39) | EPHX2ALDH1A1CNR1CNR2TAF1 | |
| SCHEMBL23116402 | 0.86 | EPHX2 (0.44) | EPHX2ALDH1A1CNR1CNR2TAF1 | |
| SCHEMBL22729445 | 0.86 | EPHX2 (0.44) | EPHX2ALDH1A1CNR1CNR2TAF1 | |
| SCHEMBL22729822 | 0.85 | ALDH1A1 (0.46) | ALDH1A1CNR2TAF1CECR2BRD9 | |
| SCHEMBL22729682 | 0.85 | LIPG (0.53) | ALDH1A1TAF1CECR2BRD9LIPG | |
| SCHEMBL22729684 | 0.82 | SPR (0.44) | EPHX2ALDH1A1KDM4EKMT2A | |
| SCHEMBL22729552 | 0.82 | TAF1 (0.44) | EPHX2ALDH1A1CNR2TAF1CECR2 | |
| SCHEMBL22729800 | 0.81 | ALDH1A1 (0.55) | ALDH1A1CNR1CNR2NPC1RAB9A | |
| SCHEMBL22729680 | 0.80 | LIPG (0.43) | ALDH1A1CNR1CNR2TAF1CECR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | EPHX2 2093/4885ALDH1A1 2626/4885FAAH 601/4885 |
| US-11459325-B2 | Heterocyclic compound | GBA1, GBA2, GALC | EPHX2 2011/4885ALDH1A1 2660/4885FAAH 581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.