Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNB4 | O00305 | 4/20 | 0.43 |
| ▸ | CACNA1A | O00555 | 4/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.43 |
| ▸ | CACNG3 | O60359 | 4/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.43 |
| ▸ | CACNB3 | P54284 | 4/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.43 |
| ▸ | CACNG7 | P62955 | 4/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.43 |
| ▸ | CACNG1 | Q06432 | 4/20 | 0.43 |
| ▸ | CACNB2 | Q08289 | 4/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.43 |
| ▸ | CACNA1E | Q15878 | 4/20 | 0.43 |
| ▸ | CACNA2D4 | Q7Z3S7 | 4/20 | 0.43 |
| ▸ | CACNA2D3 | Q8IZS8 | 4/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29839399 | 1.00 | CACNB4 (0.43) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL22729487 | 0.84 | FPR2 (0.43) | CNR1KCNH2MCHR1EPHX2ALDH1A1 | |
| SCHEMBL22729645 | 0.77 | CACNB4 (0.45) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL29839340 | 0.77 | CACNB4 (0.45) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL22729864 | 0.77 | LMNA (0.41) | LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL22729533 | 0.76 | MAPT (0.42) | LMNANPSR1 | |
| SCHEMBL1810921 | 0.75 | CACNB4 (0.51) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL29839344 | 0.74 | SCN9A (0.41) | CNR1LMNAMAPK1KMT2AALDH1A1 | |
| SCHEMBL22729549 | 0.74 | SCN9A (0.41) | CNR1LMNAMAPK1KMT2AALDH1A1 | |
| SCHEMBL1809256 | 0.72 | MGLL (0.68) | LMNACYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | CACNB4 2215/4885CACNA1A 1318/4885CACNA1G 1454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.