SCHEMBL22730146

SCHEMBL22730146

N#Cc1cccc(F)c1-c1c(F)cncc1C#N

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 14/20 0.40
CYP11B1 P15538 13/20 0.40
BCAT1 P54687 1/20 0.40
HTT P42858 1/20 0.39
GABRA1 P14867 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRA5 P31644 2/20 0.36
GABRA3 P34903 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21928401 0.76 CYP11B1 (0.48) CYP11B2CYP11B1BCAT1GABRG2GABRB3
SCHEMBL792287 0.74 TYK2 (0.38) CYP11B2CYP11B1BCAT1HTTGABRA1
SCHEMBL15124655 0.73 IDO1 (0.48) BCAT1
SCHEMBL1586204 0.73 CLK4 (0.41) CYP11B2BCAT1HTTGABRA1GABRG2
SCHEMBL29912400 0.73 CLK4 (0.41) CYP11B2BCAT1HTTGABRA1GABRG2
SCHEMBL30725740 0.72 CYP11B1 (0.42) CYP11B2CYP11B1GABRA1GABRG2GABRB3
SCHEMBL1605889 0.72 PDK2 (0.46) CYP11B2CYP11B1BCAT1GABRA1GABRG2
SCHEMBL17436331 0.71 CYP11B2 (0.41) CYP11B2CYP11B1BCAT1GABRA1GABRG2
SCHEMBL2650897 0.70 GABRA1 (0.36) CYP11B2CYP11B1BCAT1GABRA1GABRG2
SCHEMBL2651420 0.70 CUL4A (0.39) CYP11B2CYP11B1BCAT1GABRA1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200381631-A1 COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200381631-A1 COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS DRD5, DRD1, DRD2 CYP11B2 1432/4885CYP11B1 1287/4885BCAT1 4012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.