Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058186 | 0.85 | APLNR (0.39) | CTSKKDM4ANAMPTNR1H4CYP1A2 | |
| SCHEMBL28387978 | 0.75 | KDM4A (0.42) | KDM4ANAMPTL3MBTL1KDM4ELMNA | |
| SCHEMBL8235172 | 0.75 | EPHX2 (0.49) | KDM4AL3MBTL1NR1H4CYP1A2KDM4E | |
| SCHEMBL30914650 | 0.75 | KDM4A (0.42) | KDM4ANAMPTL3MBTL1NR1H4CYP1A2 | |
| SCHEMBL22862323 | 0.74 | HDAC3 (0.43) | NAMPTAAK1CYP3A4PCSK9 | |
| SCHEMBL216619 | 0.74 | HSD17B10 (0.60) | CTSKKDM4E | |
| SCHEMBL18136745 | 0.74 | KDM4A (0.44) | KDM4ANAMPTL3MBTL1KDM4ELMNA | |
| SCHEMBL4153485 | 0.74 | KDM4A (0.44) | KDM4ANAMPTL3MBTL1KDM4ELMNA | |
| SCHEMBL3028012 | 0.74 | PKM (0.45) | KDM4AL3MBTL1CYP1A2KDM4ECYP3A4 | |
| SCHEMBL1810190 | 0.74 | NR1H4 (0.45) | KDM4AL3MBTL1NR1H4CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3744722-A1 | ß-LACTAMASE INHIBITOR AND USE THEREOF | Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) | 2020-12-02 | — | — | EP | disclosed |