Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22986774 | 0.87 | CTSK (0.35) | HSD11B1CYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL15295730 | 0.87 | CTSK (0.35) | HSD11B1CYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL22946500 | 0.85 | CTSK (0.37) | HSD11B1CYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL16439228 | 0.84 | CTSK (0.47) | HSD11B1CYP2C9EPHX1CTSKCA1 | |
| SCHEMBL2082768 | 0.81 | ALDH1A1 (0.36) | HSD11B1CYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL2082769 | 0.81 | ALDH1A1 (0.36) | HSD11B1CYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL17574400 | 0.80 | MEN1 (0.36) | HSD11B1CYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL28403064 | 0.80 | MEN1 (0.36) | HSD11B1CYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL9073870 | 0.80 | ALDH1A1 (0.36) | HSD11B1CYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL7299678 | 0.80 | ALDH1A1 (0.36) | HSD11B1CYP2C9ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3744722-A1 | ß-LACTAMASE INHIBITOR AND USE THEREOF | Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) | 2020-12-02 | — | — | EP | disclosed |