SCHEMBL2273185

SCHEMBL2273185

CC1(C)OCC(CBr)(CBr)CO1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNA4 P22459 1/20 0.38
KCNA1 Q09470 1/20 0.38
KCNAB1 Q14722 1/20 0.38
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18589278 0.87 KCNA4 (0.34) KCNA4KCNA1KCNAB1
SCHEMBL12769174 0.85 EPHX1 (0.41) KCNA4KCNA1KCNAB1EPHX1
SCHEMBL22467787 0.82 EPHX1 (0.33) KCNA4KCNA1KCNAB1EPHX1
SCHEMBL18919236 0.79 KCNA4 (0.35) KCNA4KCNA1KCNAB1
SCHEMBL31659396 0.78 KCNA4 (0.38) KCNA4KCNA1KCNAB1EPHX1
SCHEMBL9339560 0.76
SCHEMBL11912902 0.74 EPHX1 (0.38) KCNA4KCNA1KCNAB1EPHX1
SCHEMBL15899256 0.73
SCHEMBL31399346 0.73
SCHEMBL10512380 0.72 KCNA4 (0.33) KCNA4KCNA1KCNAB1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10808003-B2 Amphipathic molecule based on tandem malonate and use thereof INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2020-10-20 US claimed
US-20200048297-A1 NOVEL AMPHIPATHIC MOLECULE BASED ON TANDEM MALONATE AND USE THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2020-02-13 US claimed
US-20190169218-A1 AMPHIPATHIC COMPOUND HAVING NOVEL PENTA-SACCHARIDE HYDROPHILIC GROUP AND USE THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2019-06-06 US claimed
EP-3023448-B1 POLYKETONE POLYMERIZATION CATALYST HYOSUNG CHEMICAL CORP (KR) 2018-11-14 EP claimed
US-20160333036-A1 POLYKETONE POLYMERIZATION CATALYST Hyosung Chemical Corporation (KR) 2016-11-17 US claimed
EP-3023448-A1 POLYKETONE POLYMERIZATION CATALYST Hyosung Corporation (KR) 2016-05-25 EP claimed
WO-2025023235-A1 BRANCHED MULTI-HYDROXYL-PROTECTING OLIGOMER, LINKED BODY BONDED THEREWITH, AND BRANCHED MULTI-HYDROXYL OLIGOMER OBTAINED BY DEPROTECTING SAID LINKED BODY トモイケ バイオ リミテッド 2025-01-30 WO disclosed
CN-119119119-A Water-soluble polyketone catalyst ligand and synthesis method thereof 黄河三角洲京博化工研究院有限公司 2024-12-13 CN disclosed
CN-114929839-B Liquid crystal composition, liquid crystal display element and compound 石家庄诚志永华显示材料有限公司 2024-08-09 CN disclosed
US-11999892-B2 Liquid crystal composition, liquid crystal display element and compound DIC CORPORATION (JP) 2024-06-04 US disclosed
EP-4194434-A1 POLYURETHANE, METHOD FOR PRODUCING POLYURETHANE, ELECTROCONDUCTIVE PASTE COMPOSITION, ELECTROCONDUCTIVE WIRE, AND METHOD FOR PRODUCING ELECTROCONDUCTIVE WIRE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-14 EP disclosed
US-20230131540-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT AND COMPOUND DIC CORPORATION (JP) 2023-04-27 US disclosed
US-20230131540-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT AND COMPOUND DIC CORPORATION (JP) 2023-04-27 US disclosed
US-4665197-A NITRIC ACID OXIDATION OF 3,3-BIS/HYDROXYMETHYL/AZETIDINE/ SHELL OIL COMPANY (US) 1987-05-12 US disclosed
US-4591457-A Arysulphonyl azetidine compounds used as intermediates SHELL OIL COMPANY (US) 1986-05-27 US disclosed
US-4569795-A Arylsulphonyl azetidine compounds, their preparation and their use as intermediates SHELL OIL COMPANY (US) 1986-02-11 US disclosed
EP-0168852-A1 Azetidine derivatives and their preparation SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1986-01-22 EP disclosed
EP-0165636-A1 Process for preparing azetidine derivatives and intermediates therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1985-12-27 EP disclosed
US-4183862-A Polycyclic polyoxyalkylene compounds THE DOW CHEMICAL COMPANY (US) 1980-01-15 US disclosed
US-4113739-A Process for preparation of (poly)cyclic polyethers THE DOW CHEMICAL COMPANY (US) 1978-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048297-A1 NOVEL AMPHIPATHIC MOLECULE BASED ON TANDEM MALONATE AND USE THEREOF MAL2, LNPK, ANXA6 KCNA4 2699/4885KCNA1 2233/4885KCNAB1 2906/4885
US-20160333036-A1 POLYKETONE POLYMERIZATION CATALYST PNKP, PANK1, DMPK KCNA4 1986/4885KCNA1 1551/4885KCNAB1 2086/4885
US-10808003-B2 Amphipathic molecule based on tandem malonate and use thereof MAL2, LNPK, TSPO KCNA4 2796/4885KCNA1 2169/4885KCNAB1 3024/4885
US-20190169218-A1 AMPHIPATHIC COMPOUND HAVING NOVEL PENTA-SACCHARIDE HYDROPHILIC GROUP AND USE THEREOF UGCG, APMAP, GID4 KCNA4 2205/4885KCNA1 2542/4885KCNAB1 2850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.