Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29942154 | 1.00 | BACE1 (0.35) | BACE1MAPTL3MBTL1GRM2LMNA | |
| Benzoic Acid SCHEMBL29120393 | 0.83 | DAO (0.42) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL28698487 | 0.82 | — | — | |
| SCHEMBL28682480 | 0.75 | LMNA (0.33) | LMNA | |
| SCHEMBL5355939 | 0.74 | — | — | |
| SCHEMBL289345 | 0.74 | — | — | |
| SCHEMBL289346 | 0.74 | ALDH1A1 (0.46) | MAPT | |
| SCHEMBL346282 | 0.74 | — | — | |
| SCHEMBL4615662 | 0.74 | F9 (0.30) | — | |
| SCHEMBL10591064 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514802-A1 | IMIDAZOLE DERIVATIVES AS ALK5 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-03-05 | — | — | EP | disclosed |
| US-20240059703-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. | 2024-02-22 | — | — | US | disclosed |
| WO-2023208986-A1 | IMIDAZOLE DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-11-02 | — | — | WO | disclosed |
| CN-111710802-B | Display panel, preparation method of display panel and display device | 云谷（固安）科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110734451-B | Semiconductor material, preparation method thereof and organic light-emitting diode | 北京大学深圳研究生院 | 2022-07-22 | — | — | CN | disclosed |
| CN-114163429-B | Thermochromic material with single-crystal violet lactone structure, color developing composition, preparation method and application of thermochromic material | 北京高德品创科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114163450-B | Thermochromic material with single rhodamine structure, developing composition, preparation method and application thereof | 北京高德品创科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114163450-A | Thermochromic material with single rhodamine structure, developing composition, preparation method and application thereof | 北京高德品创科技有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114163429-A | Thermochromic material with single-crystal violet lactone structure, color developing composition, preparation method and application of thermochromic material | 北京高德品创科技有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-20210323987-A1 | Methods for the Synthesis of Heteroatom Containing Polycyclic Aromatic Hydrocarbons | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-21 | — | — | US | disclosed |
| WO-2007081991-A2 | NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007016392-A2 | BENZOTHIAZOLE AND AZABENZOTHIAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |
| US-7138484-B2 | Method for producing polymerized hydrocarbon | JFE CHEMICAL CORPORATION (JP) | 2006-11-21 | — | — | US | disclosed |
| US-20050075478-A1 | Method for producing polymerized hydrocarbon | JFE CHEMICAL CORPORATION (JP) | 2005-04-07 | — | — | US | disclosed |
| EP-1520846-A1 | Method for producing polymerized hydrocarbon | JFE Chemical Corporation (JP) | 2005-04-06 | — | — | EP | disclosed |
| US-4786739-A | SULFIDING | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0146610-A4 | SUBSTITUTED BENZOPENTATHIEPINS, PROCESS THEREFOR AND INTERMEDIATES. | DU PONT (US) | 1986-02-20 | — | — | EP | disclosed |
| US-4571404-A | PLANT HERBICIDE, FUNGICIDE OR VIRICIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-02-18 | — | — | US | disclosed |
| EP-0146610-A1 | SUBSTITUTED BENZOPENTATHIEPINS, PROCESS THEREFOR AND INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |
| WO-1984004921-A1 | SUBSTITUTED BENZOPENTATHIEPINS, PROCESS THEREFOR AND INTERMEDIATES | DU PONT (US) | 1984-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323987-A1 | Methods for the Synthesis of Heteroatom Containing Polycyclic Aromatic Hydrocarbons | AHR, PAH, ALKBH3 | BACE1 3878/4885MAPT 4225/4885L3MBTL1 3756/4885 |
| US-20240059703-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | KRAS, HRAS, APC | BACE1 3827/4885MAPT 4629/4885L3MBTL1 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.