Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | S100A4 | P26447 | 2/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503289 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2S100A4EDNRAMAPTLMNA | |
| SCHEMBL10843954 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2EDNRAMAPTLMNATP53 | |
| SCHEMBL15580875 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2EDNRAMAPTLMNATP53 | |
| SCHEMBL16689762 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2EDNRAMAPTLMNATP53 | |
| SCHEMBL11549835 | 0.72 | S100A4 (0.54) | SMN1; SMN2S100A4EDNRAMAPTLMNA | |
| SCHEMBL2300494 | 0.69 | SMN1; SMN2 (0.38) | SMN1; SMN2S100A4EDNRAMAPTLMNA | |
| SCHEMBL12474357 | 0.68 | SMN1; SMN2 (0.52) | SMN1; SMN2EDNRAMAPTLMNATP53 | |
| SCHEMBL20429730 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2EDNRAMAPTLMNATP53 | |
| SCHEMBL22721829 | 0.67 | MEN1 (0.58) | SMN1; SMN2EDNRAMAPTLMNATP53 | |
| SCHEMBL1306039 | 0.65 | SMN1; SMN2 (0.42) | SMN1; SMN2EDNRALMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020241715-A1 | POLAR GROUP-CONTAINING OLEFIN COPOLYMER | 国立大学法人東京大学 | 2020-12-03 | — | — | WO | disclosed |