SCHEMBL1306039

SCHEMBL1306039

c1ccc(C2C3=C4C5=C6C(=C3C62)C4C5c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42
EDNRA P25101 1/20 0.42
TSHR P16473 1/20 0.39
MAOB P27338 12/20 0.39
MAOA P21397 11/20 0.39
KDM1A O60341 9/20 0.39
CYP2C19 P33261 4/20 0.38
CYP2B6 P20813 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C9 P11712 2/20 0.38
LMNA P02545 2/20 0.38
TAAR1 Q96RJ0 2/20 0.38
CYP3A4 P08684 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CYP2A6 P11509 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2C P28335 1/20 0.38
ADRA1A P35348 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10843954 0.71 SMN1; SMN2 (0.65) SMN1; SMN2EDNRATSHRCYP1A2LMNA
SCHEMBL22012817 0.67 SMN1; SMN2 (0.38) SMN1; SMN2EDNRACYP1A2LMNACYP3A4
SCHEMBL2031804 0.67 HDAC4 (0.46) TSHRMAOBMAOAKDM1ACYP2C19
SCHEMBL31041077 0.67 HDAC4 (0.46) TSHRMAOBMAOAKDM1ACYP2C19
SCHEMBL22732971 0.65 SMN1; SMN2 (0.52) SMN1; SMN2EDNRACYP1A2LMNACYP3A4
SCHEMBL15580875 0.65 SMN1; SMN2 (0.58) SMN1; SMN2EDNRATSHRCYP1A2LMNA
SCHEMBL12474357 0.65 SMN1; SMN2 (0.52) SMN1; SMN2EDNRACYP1A2LMNACYP3A4
SCHEMBL16689762 0.65 SMN1; SMN2 (0.58) SMN1; SMN2EDNRATSHRCYP1A2LMNA
SCHEMBL30149221 0.65 HDAC4 (0.44) TSHRMAOBMAOAKDM1ACYP2C19
SCHEMBL7556279 0.63 LMNA (0.46) MAOBMAOAKDM1ACYP2C19CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12044872-B2 Method for generating alignment on top of a liquid crystal polymer material Rolic Technologies AG (CH) 2024-07-23 US disclosed
US-12012382-B2 Polymerizable liquid crystal having a carbazole core Rolic Technologies AG (CH) 2024-06-18 US disclosed
US-12006463-B2 Polymerizable liquid crystal having a quinoxaline-hydrazone core Rolic Technologies AG (CH) 2024-06-11 US disclosed
US-11952524-B2 Compositions of polymerizable liquid crystals Rolic Technologies AG (CH) 2024-04-09 US disclosed
EP-3175493-B1 ENCAPSULATION STRUCTURE FOR AN OLED DISPLAY INCORPORATING ANTIREFLECTION PROPERTIES BASF COATINGS GMBH (DE) 2024-03-06 EP disclosed
EP-3990568-B1 NEW POLYMERIZABLE LIQUID CRYSTAL HAVING A QUINOXALINE-HYDRAZONE CORE ROLIC TECH AG (CH) 2023-11-15 EP disclosed
US-11702595-B2 Polymerizable liquid crystal Rolic Technologies AG (CH) 2023-07-18 US disclosed
EP-3126883-B1 OPTICAL DEVICES WITH PATTERNED ANISOTROPY INCORPORATING PARALLAX OPTIC ROLIC TECH AG (CH) 2023-07-12 EP disclosed
US-20220228063-A1 NEW POLYMERIZABLE LIQUID CRYSTAL Rolic Technologies AG (CH) 2022-07-21 US disclosed
US-20220163853-A1 PHOTO-ALIGNABLE POSITIVE C-PLATE RETARDER Rolic Technologies AG (CH) 2022-05-26 US disclosed
US-20150109597-A1 FAST GENERATION OF ELEMENTS WITH INDIVIDUALLY PATTERNED ANISOTROPY ROLIC AG (CH) 2015-04-23 US disclosed
US-20140226115-A1 PHOTO-ALIGNMENT LAYERS WITH STRONG UV-DICHROISM ROLIC AG (CH) 2014-08-14 US disclosed
EP-2067064-B1 VOLUME PHOTO-ALIGNED RETARDER ROLIC AG (CH) 2014-06-11 EP disclosed
US-8574454-B2 Patternable liquid crystal polymer comprising thio-ether units ROLIC AG (CH) 2013-11-05 US disclosed
EP-2094815-B1 PATTERNABLE LIQUID CRYSTAL POLYMER COMPRISING THIO-ETHER UNITS ROLIC AG (CH) 2012-06-27 EP disclosed
US-8054411-B2 Volume photo-aligned retarder ROLIC AG (CH) 2011-11-08 US disclosed
US-20100266814-A1 PHOTOALIGNMENT COMPOSITION ROLIC AG (CH) 2010-10-21 US disclosed
US-20100266821-A1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS ROLIC AG (CH) 2010-10-21 US disclosed
US-20100059709-A1 PATTERNABLE LIQUID CRYSTAL POLYMER COMPRISING THIO-ETHER UNITS ROLIC AG (CH) 2010-03-11 US disclosed
US-20100026935-A1 VOLUME PHOTO-ALIGNED RETARDER ROLIC AG (CH) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12012382-B2 Polymerizable liquid crystal having a carbazole core FZD7, CCL11, SGK2 SMN1; SMN2 4742/4885EDNRA 3262/4885TSHR 4670/4885
US-12006463-B2 Polymerizable liquid crystal having a quinoxaline-hydrazone core AQP1, AQP4, HCN1 SMN1; SMN2 4753/4885EDNRA 3066/4885TSHR 4748/4885
US-20100266821-A1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS ETV6, TERB1, VCL SMN1; SMN2 4497/4885EDNRA 2772/4885TSHR 2049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.