SCHEMBL2273308

SCHEMBL2273308

CCN(CC)CCCC[SiH](Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.36
HRH4 Q9H3N8 2/20 0.32
HRH3 Q9Y5N1 2/20 0.32
KCNH2 Q12809 4/20 0.32
ALDH1A1 P00352 1/20 0.32
KDM4E B2RXH2 1/20 0.32
SLC2A1 P11166 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CHRM2 P08172 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD1 P21728 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
ADRA1A P35348 1/20 0.30
OPRM1 P35372 1/20 0.30
DRD3 P35462 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2102240 0.92 SIGMAR1 (0.33) SIGMAR1KCNH2KDM4ESLC2A1NPSR1
SCHEMBL2269180 0.83 SIGMAR1 (0.35) SIGMAR1HRH4HRH3KCNH2ALDH1A1
SCHEMBL2100424 0.81 MEN1 (0.30)
SCHEMBL2274508 0.81 SIGMAR1 (0.34) SIGMAR1HRH4HRH3KCNH2ALDH1A1
SCHEMBL2271684 0.79 SIGMAR1 (0.33) SIGMAR1HRH4HRH3KCNH2
SCHEMBL2275406 0.78 SIGMAR1 (0.33) SIGMAR1
SCHEMBL2267718 0.78 SIGMAR1 (0.36) SIGMAR1
SCHEMBL234338 0.78 SIGMAR1 (0.48) SIGMAR1HRH4HRH3KCNH2ALDH1A1
SCHEMBL15052279 0.78 SIGMAR1 (0.48) SIGMAR1HRH4HRH3KCNH2ALDH1A1
SCHEMBL25224116 0.75 SIGMAR1 (0.36) SIGMAR1HRH4HRH3KCNH2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed